Thinking about it now, comedies and dramas are a little easier to do without commercials, considering how premium cable set that model decades ago.
It would be interesting to see how a Netflix game show pulls off transitioning from one round/competition to another without the commercial break. I suppose you could simply have the host say "Edna wins the game and will be back to play for $20,000 in one moment!" (cue star wipe) "Annnnd we're back!"
Maybe segue the two by throwing in a fee plug or promo similar to what Wheel does when it talks about the Wheelmobile coming to your town soon...
ETA: I forgot Where in the World/Time is Carmen Sandiego used little musical segues...