This is a very good question. Nearly every show I thought of I've had to really think if it was consistently man/men vs. Woman/women. I want to say both the original CBS Password was as well as the original $10K Pyramid, but I may be confusing the men versus women CELEBRITY pairings and not necessarily the contestants.
Card Sharks, not counting the Game Show Hosts tournament? Although I think I’ve seen at least one same gender match. I honestly can’t remember.