When reviewing something in the pharmaceutical realm about 12 years ago, I flagged the offensive demonym when it was used to describe side effects and certain populations. It went through multiple levels in my department, but they made the unfortunate decision to "retain the term because it was cited in the source," a decades-old medical article.
However, Orient is not only geographic designation, but one that has cultural significance. But, if they are overly cautious on 40-year old prize copy, I'm okay with that. (And thankfully, the word flokati is not offensive.)