Mine goes to the original board game version of Cullen TPIR - I only played it once; IIRC, each player had a set of cards with numbers from 1 to 15, and whoever "bid" the higher number won whatever was on the next prize card.
Runner-up is the original Milton Bradley version of Barker TPIR; the prices bared little resemblance to actuality - cars could range from $1023 to $9876. In addition, the IUFB game consisted of each player with cards from 1 to 6, and whoever played the highest card not matched by another player won.
MB Family Feud gets an honorable mention; all games were single-single-double, so if you won the first two and got control of the third, you played, and intentionally got three strikes to make it impossible for the other team to win.
(Bonus question: the box art had a game in progress - what was the question? Name a man's first name that begins with R)
Also, Password, but that gets an asterisk; pretty much all it had was pairs of cards with identical 5-word lists, a pair of red lenses so you could only see one word on a card at a time, and a dial that could be set from 1 to 10...but when you think about it, that's all that Password was.